Why Am I Not Getting Pregnant Again ?

by Dr Agilan Arjunan, Fertility Specialist, KL Fertility Centre ( Malaysia)


Mrs M walked into the clinic with her beautiful daughter Maya, aged 5 . She is a happily married woman and conceived Maya within their first 6 months of marriage. Her pregnancy was well and Maya was delivered via a caesarean delivery.

The obvious question popped up in my mind, “ How can I help you ?”

“ Well one ain’t enough and we have been trying for a second child for the past one and a half years. I just don’t understand why i am not getting pregnant. I got pregnant with Maya easily. Surely we are not suffering from infertility. But why it is not happening again ?”

She is just one out of many women who find it difficult to believe that they are struggling for a second child or what is medically known as secondary subfertility.

What leads to secondary subfertility ? Let’s find out why.

Age factor

In a natural pregnancy , age is an important determinant of success rate. This is mainly because a woman’s egg number and egg quality declines with age. Generally,  a woman’s fertility start to decline rapidly after the age of 35-37 years old compared to when they were younger. At a younger age, fertility declines more slowly.

This is the reason why doctors ( and your mother and mother in-law too ! ) will advise you to compete your family earlier than later. Thus, your chances to conceive for the second time is not similar to when your had your first child.

Ovarian reserve ( egg numbers)

A woman’s age do play a crucial role in her ovarian reserve. Ovarian reserve means the number of eggs that you are left with , which correlates with your chances to get pregnant. The lower the ovarian reserve, the lower your chances to get pregnant.

Besides age, there are other factors which can decrease your ovarian reserve.

Ovarian surgery ( for ovarian cyst) and endometriosis can decrease your egg numbers. If you have previous surgery to your ovary and find it difficult to conceive again, maybe it’s time to see your doctor.

Ovulation Problem

Ovulation is crucial for a natural conception. When ovulation is irregular , it increases your difficulty to get pregnant naturally simply because you can not time your ‘fertile’  window accurately.

But why ovulation become irregular now and not before when you conceived your first child ?

Your weight has an effect on your ovulation. If you have put on weight after your first child, it can affect your ovulation and your monthly period cycles.

For some who have been diagnosed with Polycystic Ovarian Syndrome (PCOS) , period irregularity may start later in life . In PCOS , the woman is not ovulating regularly.

In this situation, once all the other causes are excluded, the simplest thing to do is to make the ovulation regular. In most cases, weight reduction together with some fertility medication is sufficient.

Tubal factor

Women have a pair of Fallopian tubes attached to the womb. This tube picks up the ovulated egg and fertilisation of the egg by the sperm happens in the tube.

If the tubes are damaged or blocked, chances to get pregnant naturally is much reduced or impossible ( in the case of bilateral blocked tubes).

Fallopian tubes are at risk of being damaged or blocked when a woman undergoes any kind of pelvic surgery including a caesarean section, ovarian cyst removal or removal of a uterine fibroid.

Pelvic infections ( such as Chlamydia) can also lead to tubal blockage. Thus, a woman with these risk factors should check the patency of their tubes .


Endometriosis is not an uncommon cause of secondary subfertility. Endometriosis can lead to ovarian cyst , which can have a direct negative effect on egg numbers.

Endometriosis can also lead to tubal blockage due to continuos process of bleeding and scar formation.

While there is no magic treatment that can eliminate endometriosis completely, if diagnosed early , it can be controlled while in some cases, fertility treatment offered before the condition worsens.

Uterine factor

The womb or the uterus , is rarely the cause of subfertility. If you had successfully delivered a child before, it means that your uterus is able to carry a pregnancy.

However, after a major uterine surgery such as removal of numerous uterine fibroids , the anatomy of the uterus can be distorted and the lining of the uterus where the pregnancy implants can be damaged.

Another common uterine factor is a gynaecological condition called adenomyosis. In this condition , the uterus is gradually getting ‘swollen’ . Severe adenomyosis has been linked with reduced fertility.

Sperm quality

To have a successful pregnancy , you need a healthy egg and a healthy sperm. Even though male fertility declines slowly than their female partner, sperm quality is still an important factor in secondary subfertility.

Environmental factors such as cigarette smoke, unhealthy diet and pollutants are known to reduce the quality of sperm. Thus it is important for male partners to get themselves checked together with their wives.


Smoking, for both women and men, has adverse effect on their fertility. Long term smoking can lead to poorer egg quality. Likewise, smoking also reduces men’s sperm quality even though his sperm quantity is normal.

So, you could have easily conceived your first child, but continuous smoking can make it harder to conceive your second child.


Stress is widely linked to subfertility. It’s not only work related stress, but stress of caring for your first child.

You may have sleep deprivation, time pressure and pressure juggling between work and child care. These can make it more challenging to try for a baby during the fertile period of the woman.

Change in health status

The older you get , chances are that you may have developed health conditions such as high blood  pressure and diabetes. When these conditions are not well controlled, it reduces your fertility. It is important to have regular health check ups and initiate early intervention if needed.

The above are some common causes of secondary subfertility . If you are one of them, take the necessary step today to get yourself checked.

Last but not least , remember : “You have done it once, and you can do it again.”

10 responses to “Why Am I Not Getting Pregnant Again ?”

  1. Hi doctor,
    I’m Mrs Rina here.Im 34 this year.My first child is 6 yrd old this year.We gt married in June 2010 n conceived my child in March 2011.We hv been trying for 2nd but failed all this while.2 years ago i was diagnosed with hypothyroidism.Current im taking o.o5 mg thyroxine daily.Does this affect my pregnancy?Other thn this i dont hv other health prob.My weight is 65 kg n height is 165cm.I do suffer every mth due to terrible menstruation cramps n pain but doc who scanned n checked said im completely fine.

    • Hi Rina. Uncontrolled thyroid disease can have an effect on fertility . Would you mind giving me your email address ? I will email you with more information. Thank you and take care Rina.

  2. Hallo Doctor,
    My name is Rini and I’m 41yrs old. My son is 8yrs old will be 9yrs old soon on the 14th of march. I’ve been trying to have our 2nd child since my son was 1yr old. Just the normal program with the Doctors every mth checked and ate some of the medicines they gave me for several years then off then continue again .. then insemination several times but failed. I think around 6/7 times. So far the doctors said that i’m ok .. my husband is ok but… i really don’t know what is wrong that we can’t anymore. My monthly period now is ok again. After the last insemination 3x in a row on end of mths of year 2015 kind of screwed up my regular monthly for the whole year of 2016. I still want to try this time IV i think… but i really want to know what is really going on this time.. what should i do…?

  3. Hi doctor…I married on oct2012, conceived on November 2012, normal delivery. In 2014 Dec I got miscarriage at 7weeks, then I was diagnosed as hypothyroidism and high prolactin..since that I am on hormone tablets and controlled well with regular check up, but still I can’t get pregnant. I am 34 yrs.
    Thank you.

    • Hi Anila. Since your thyroid and prolactin level is well controlled, you should look for other causes that can lead to secondary sub fertility. Can I have your email address pls?

  4. Hi doc..We got married on August 2013 & conceived on February 2014. After my first child turns two, we had planned our ttc journey for 2nd child. Now it is almost 8 months, and suddenly today, my period, looks ‘funny’. I have regular & normal period, but for this month, it is only spot of blood. Should I be worry? I know it is only 8 months but it got me worry when my period looks irregular for this month..any advise, doc?

    • Hi, it looks like not you usual period flow. Sometimes a corpus luteal cyst ( post -ovulation cyst) can cause this. Please see a gynaecologist to rule out this possibility. Thanks.

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